I'm genuinely surprised a doctor gave you this drug considering your other conditions. I've just finished a three month Zoladex shot (similar to Lupron) and had to see my doctor about side effects. I don't usually suffer from depression but on Zoladex I plummeted into a deep dark place in the last few weeks, it was scary. Please, please go back to your doctor straight away. I don't know if add-back therapy will do the trick but if the doctor says it won't work, ask to have the implant removed or just don't have the next one. There has to be a safer way for you to get treatment. I'm interested to hear how you proceed and I want to know you're doing ok, so please post again soon.