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Would You Try Lupron Again? Why Or Why Not?
A MyEndometriosisTeam Member asked a question 💭

Hello All,

I wanted to ask a few questions about some concerns I have about @@Lupron injections. I've had pelvic pain for over ten years, and I was officially diagnosed with stage 3-4 endometriosis last year at 26 after three years of pelvic floor dysfunction. I had significant large endometriomas on my right ovary, some damage to my left, endo on my ligaments, some on my bladder, and endo on my cul-de-sac. My gyno who is an endometriosis specialist put me on a combined birth control, but I… read more

posted January 15, 2018 (edited)
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A MyEndometriosisTeam Member

I took Lupron depot twice. First time was 20 years ago without an add back. Couldn't finish series of shots due to side effects. Second time was last year. I did take an add back med. Which helped w side effects. However, as soon as Lupron wore off , the Endo seemed more unbearable. If you decide to do Lupron make sure you take an add back to deal with side effects! I found that as soon as I went off of it, Endo symptoms returned w a vengence. Now trying Orilissa that has taken away all pain. Much happier and I am also taking an add back with it too.

posted November 19, 2018 (edited)
A MyEndometriosisTeam Member

It worked great for me while I was taking it. Had slight side effects morning too bad. But, as soon as I stopped it was back worse than ever. But while taking it helped a lot.

posted August 20, 2018
A MyEndometriosisTeam Member

I would not. I had the 3 month injection right after my first lap last year. I had the night sweats, mood swings, insomnia etc but it did relief my endo symptoms until the end of the 3 months. Then everything came back with a vengeance. I kinda feel robed because I didn't even realize the pain I was having on a day to day basis until the Lupron hid it. I got just a little bit of what its like to live a normal life and then it was yanked back. Its been almost a year since (In 3 weeks it will be 12 months) my one 3 month injection and I still have not ovulated. I still have the mood swings, irritability, insomnia, foggy thoughts, and fatigue only to have to deal with the day to day endo pains too. I found out after, and I did my research too online, that 12 months post Lupron 63% of women had not regained their pre-Lupron ovarian function. Lupron only hides the problem instead of treating it. I will say I did not experience some of the more extreme side effects such as joint pain, weight gain, migraines...

posted February 19, 2018
A MyEndometriosisTeam Member

I took the 3 month shot twice and it has been a nightmare. It started out ok, just the hot flashes and such. It did help my endometriosis pain and when I went to get my 2nd shot I told my nurse that it was all good and working great. About a month and a half after the 2nd shot everything went downhill. All over body aches. Like flu body aches but no flu. Horrible spine, neck and shoulder pain. My tailbone feels like it is being jammed into my hips and when I lay down I feel like I am being crushed. I haven't had an injury, but some days I can barely walk up my steps by the time I get home from work or even lift my arms to reach my coffee pot. I see my doctor again on Monday and he is amazing. He has helped me for 20 years. I do believe he suggested this to me in an effort to help. Unfortunately I think I just got the bum end of the side effects of the Lupron. Everyone is different but please use your resources before you decided what is best for you.

posted September 19, 2018

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