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Lupron?
A MyEndometriosisTeam Member asked a question 💭

Has anyone used Lupron before. I am considering it but would love some feedback.

posted May 5, 2022
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A MyEndometriosisTeam Member

There’s a ton of negativity towards Lupron and reading about it terrified me… I did lupron depo 2x prior to an IVF cycle (2 months and 1 month) to calm the endo down and allow my ovaries to respond better to the stimulations, and it worked really well… So i am grateful for that. I am back on it pre-op and its not been bad. I have had some hot flashes and night sweats… previously I did get near daily spotting on it, but it has made an incredible difference for my pain! Each time they’ve given me “hormonal addback” so I’m not at risk for bone density loss. I wouldn’t rave about it, but I do think it can be very useful in certain situations/stages of life. Yes there may be side effects, but with endo most of us have many symptoms anyway, so its kind of like choose which ones are better for you!? We don’t have great treatment options, so I think if your Dr thinks it could be a good option for you, you could give it a few months (the first couple weeks you may feel worse so hang in there) and see if it is right for you… and ask about hormonal addback. Good luck!

posted May 10, 2022
A MyEndometriosisTeam Member

Please don’t base your decision on people regurgitating information they’ve found about treatments they have no experience with. Do your own research.
I have been on Lupron and I did research and I do wish I had had the confidence to say it wasn’t for me because I didn’t have a good feeling about it for myself. It didn’t help my pain at all and not only did I have severe hot flashes but also pretty bad memory loss. However, it did keep my endometriosis from growing, as when they did my second surgery a year later there was much less endometriosis than they were expecting, and it kept it from causing infertility from spreading to my ovaries. Just do your own research and have an honestly talk with your doctor about the options.
Orlissa did work much better for me and had less severe side affects.

Just so you know, Lupron work by flooding your systems with progesterone (or GnRH) which causes your body to then shut down it’s own production. It’s called an agonist. It was originally developed as a treatment for prostate cancer and also is used as a transgender hormone suppression treatment.

Orlissa works by limiting your bodies own progesterone (or GnRH) production, but doesn’t flood your system with it first. It’s considered an antagonist. It’s only purpose is as a treatment for endometriosis.

I hope you figure out what’s best for you!

posted May 13, 2022
A MyEndometriosisTeam Member

This person is looking for feedback from people who have used Lupron - I hope some others are able to offer their personal experiences to help them make a decision for their own care. :)

posted May 12, 2022
A MyEndometriosisTeam Member

Every medication has potential side effects, and each person is different and will have their own unique experience. There’s actually a lot of research as it’s been prescribed for over 30 years! There is a lot of negativity and fear mongering with regards to Lupron, however it can really make a significant positive difference for many people and I wouldn’t want someone to miss out on a chance at improving their quality of life if it ends up being the right med for them!

posted May 11, 2022
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