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Real members of MyEndometriosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyEndometriosisTeam Member asked a question 💭
Watford, UK

Hi All , has anyone here been started / has taken yselty and tibolone.
I had surgery done few months ago to remove endometriomas but unfortunately it has grown back to 3cm just months post op hence the surgeon has suggested for me to start this hormone therapy.
Can you please give me some feedback on ur experiences about using this hormones as Im quite worried with side effects /risks involved such as chances of developing cancer.

December 26, 2025
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MyEndometriosisTeam

Has anyone taken Yselty and Tibolone for endometriosis after surgery?

Unfortunately, the available information doesn't include specific experiences from MyEndometriosisTeam members about Yselty (linzagolix) and Tibolone combination therapy. However, it's understandable to feel worried about starting hormone therapy Show Full Answer

Has anyone taken Yselty and Tibolone for endometriosis after surgery?

Unfortunately, the available information doesn't include specific experiences from MyEndometriosisTeam members about Yselty (linzagolix) and Tibolone combination therapy. However, it's understandable to feel worried about starting hormone therapy, especially regarding cancer risks.

Regarding hormone therapy after surgery, it's worth knowing that when hormone replacement therapy is used after endometriosis surgery (particularly if ovaries are removed), it typically doesn't cause endometriosis to come back. Most doctors recommend starting hormone therapy after surgery to reduce menopause-like symptoms such as hot flashes.

Important considerations about hormone therapy risks:

It's crucial to discuss with your doctor the specific risks of any hormone replacement therapy, which may include:
- Increased risk of breast cancer
- Deep venous thrombosis (blood clots)

The good news is that hormone replacement therapy today isn't as risky as it was in the past, but you should thoroughly review your personal risk factors with your healthcare provider before starting treatment.

Since your endometriomas have returned quickly after surgery, hormone therapy may help slow the growth of endometrial tissue and reduce symptoms. Taking time to understand your treatment options and having open conversations with your surgeon about your concerns is really important.

December 26, 2025

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