Overview

Aygestin was a prescription drug that was approved by the U.S. Food and Drug Administration (FDA) in 1973 to prevent pregnancy. Aygestin was also prescribed to treat symptoms of endometriosis. Aygestin was referred to by its drug names, norethindrone and norethisterone.

Aygestin was a contraceptive, or drug used to prevent pregnancy. Specifically, Aygestin was a progestin, a synthetic form of the hormone progesterone. Aygestin was believed to work by changing hormone levels and controlling the growth of the uterine lining.

How was it taken?

Aygestin was typically taken orally once a day. 

Side effects

Common side effects of Aygestin included changes in menstrual flow or weight, stomach upset, trouble sleeping, nausea, bloating, acne, abnormal vaginal bleeding, and swollen or painful breasts. 

Serious side effects of Aygestin included blood clots, heart attacks, strokes, high blood pressure, vision changes, and migraines. The risk of these serious side effects increased in women who smoke or are over 35. Aygestin sometimes caused birth defects if taken during pregnancy. Some people experienced worsened depression while taking Aygestin.

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Norethindrone Acetate — GoodRx