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The Vicodin brand was voluntarily pulled from the U.S. market in January 2012 following a request from the U.S. Food and Drug Administration (FDA). The FDA asked manufacturers to discontinue older formulations because they contained more than 325 milligrams of acetaminophen per tablet, which increased the risk of severe liver injury. Read more about the withdrawal here. If you’re currently taking this medication, talk to your healthcare provider about safe options for transitioning to a different treatment. |
Overview
Vicodin was a prescription drug approved by the FDA to manage pain severe enough to require an opioid, and for which other treatments are ineffective. Vicodin was a combination drug composed of hydrocodone and acetaminophen.
Hydrocodone is an opioid, or synthetic opiate, that works as a potent analgesic (painkiller). Acetaminophen is an analgesic and antipyretic (fever reducer). Both drugs are believed to work by reducing the perception of pain.
According to the National Institute on Drug Abuse, regular use of opioids — even as prescribed by a doctor — can lead to dependence. If misused, opioids can cause overdose and death.
How was it taken?
Prescribing information stated that Vicodin was taken every four to six hours. Vicodin came in tablet form.
Side effects
The FDA-approved label for Vicodin listed common side effects including drowsiness, dizziness, lightheadedness, nausea, and vomiting.
Rare but serious side effects listed for Vicodin included addiction, liver failure, severe skin and hypersensitivity reactions, respiratory depression, head injury, and acute abdominal problems.
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