@A MyEndometriosisTeam Member, research has demonstrated that Orlissa is no more effective than Lupron, Depo, and GnRH agonists and causes the exact same side effects, short and long-term.

Hun, if you're on FB, I suggest joining Nancy's Nook Endometriosis Education. I5 isn't a support group anymore but has SO much great information about endometriosis and its treatment.

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A MyEndom...

I had such a bad depression episode on orlissa that I had to cut myself off. I felt like I hated myself and the skin I live in. Clothing made me want to tear my skin off. I’m glad it works for some people but please listen to your body on any brand new drugs. I had the migraines too and it barely helped the pains. I have endo on my bowel so not sure if that’s why idly didn’t help. Good luck ❤️❤️

Mine stopped after three months but I too was pretty emotionally unstable in the first three months. Now I have really balanced out! No headaches in my case, it’s really doing well for me and my cysts have really calmed down as well. Stick with it!

About 3 months, and it only lasted for about 6 months. My pain is just as severe as it was before. It also didn’t stop my periods like my physician had hoped. At one point I bled heavily for a month straight on it

I've been on it for 10 months, and it has helped with my pain. The pain slowly went down over a few weeks. Now, pain is here and there. I did have to up my dosage on my anti-depressant, for anxiety and depression. I have headaches all the time now though.