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Real members of MyEndometriosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Anyone who's used opiate painkillers and switched to cannabis, how was it? Which was more helpful?

A MyEndometriosisTeam Member asked a question 💭

I live in Portugal which has legal medical cannabis. I'm currently on 100mg of trapentadol twice daily as the pain requires. I honestly do not like how it affects me, have concerns regarding how addictive it is and how ive seemed to develop a tolerance fairly quickly. I'm considering trying to switch to cannabis, I've used cbd oil in the past but didn't feel much improvement. Ive also smoked weed once as a teenager and know it doesn't affect me negatively (however it was recreational not taken… read more

August 20
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MyEndometriosisTeam

It's completely understandable to want to explore alternatives when a medication isn't sitting well with you — both physically and mentally. Your concerns about tolerance and dependency are valid ones worth discussing openly with your doctor.

Since CBD oil alone didn't give you much relief, it's worth knowing that full Show Full Answer

It's completely understandable to want to explore alternatives when a medication isn't sitting well with you — both physically and mentally. Your concerns about tolerance and dependency are valid ones worth discussing openly with your doctor.

Since CBD oil alone didn't give you much relief, it's worth knowing that full cannabis (containing THC alongside CBD) tends to work differently. Many MyEndometriosisTeam members have found that combination more effective than CBD alone for pain management. Here's what members have shared about cannabis for endometriosis pain:

- "I'm using CBD and THC, and they help with anxiety and pain."
- One member described cannabis as helping them wean off prescribed painkillers they'd taken for nine years.
- Another called CBD oil "a major game changer" for pain and sleep.

Research from Australia also identified cannabis as among the most effective home remedies for endometriosis pain relief. A few important things to keep in mind before making any switch:

- Don't stop tapentadol abruptly — this needs to be managed carefully with your doctor to avoid withdrawal
- Cannabis isn't regulated the same way as prescription medications, so potency and composition can vary
- Possible side effects of cannabis include nausea, fatigue, and irritability
- Drug interactions are possible, so your prescribing doctor needs the full picture

Given that you're already in the medical system in Portugal and pushing for surgery, raising this directly with your specialist is the best path forward. They can help you transition safely rather than abruptly.

August 20

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