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Real members of MyEndometriosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Hey all, has any one had some kind of skin rash or inflammation of the skin while on the Depoprovera injection?

A MyEndometriosisTeam Member asked a question 💭
Brooklyn, NY

I read that the depo shot can have a rash side effect which is apparently called the depo rash. How common is that? I keep learning of new side effects as I research and I'm trying to figure out if I should stay on this type of hormone treatment. Thank you

October 23, 2019
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Answer Summary

Members discussed their varied experiences with Depo-Provera and other hormonal treatments for endometriosis, with some finding relief from... Read more

Members discussed their varied experiences with Depo-Provera and other hormonal treatments for endometriosis, with some finding relief from pain while others experienced concerning side effects like rashes and bone loss. Several members shared that while Depo helped significantly with pain, the accompanying side effects weren't worth continuing, and one member mentioned that allergic rashes occur in about 12% of patients on similar medications like Lupron. A recurring theme was the importance of trusting your instincts about what feels right for your body, weighing pain relief against side effects, and seeking excision surgery from a vetted specialist rather than relying solely on suppressive hormonal treatments.

A MyEndometriosisTeam Member

I agree. I have been taking Nortrel continuously since June, 2005. It has helped with the pain and PMDD.

October 25, 2019
A MyEndometriosisTeam Member

All of those suppressive drugs cause bone loss and many times permanent bone loss. It has also been proven that Orilissa, Lupron, Depo, and GnRH agonists do NOT help endo in any way, shape, or form.

The gold standard of treatment is excision by a vetted endometriosis EXCISION specialist. There are not many who are experts. Many doctors say they are and then perform ablation which DOES NOT work!!

October 24, 2019
A MyEndometriosisTeam Member

Try and find right drug that works for u alot people used lurpon but it mite not be strong enough drug for u. Or it may not work with the injection u on.

October 23, 2019
A MyEndometriosisTeam Member

I know! One of the things my gyn told me that was helpful is to do what feels right because that’s important too. And treatment is less likely to work if you’re worried. But then sometimes it’s hard to know what feels right.

October 23, 2019
A MyEndometriosisTeam Member

Also, I feel like I should add a disclaimer that this is not medical advice! I'm not a doctor yet and so I can't give you medical advice. Just looked up a stat for your information :)

October 23, 2019

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Does Depo Provera help with pain?

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