Weight gain with endometriosis treatments is a real and frustrating experience that many people share. Gaining 10kg is significant and absolutely worth discussing with your doctor — especially since your eating habits haven't changed.
Ryeqo contains relugolix, estradiol, and norethisterone (a progestin). Similar Show Full Answer
Weight gain with endometriosis treatments is a real and frustrating experience that many people share. Gaining 10kg is significant and absolutely worth discussing with your doctor — especially since your eating habits haven't changed.
Ryeqo contains relugolix, estradiol, and norethisterone (a progestin). Similar medications used for endometriosis have been linked to weight gain as a side effect, and progestin-based treatments in particular are associated with this. There are a few reasons weight gain can happen while on endometriosis treatment, even when eating less:
- Fluid retention — endometriosis and hormonal treatments can cause the body to hold onto extra water, making the belly, legs, and hands appear swollen
- Hormonal shifts — changes in estrogen and progesterone levels can make weight management harder
- Reduced activity — pain and fatigue from endometriosis can make it harder to stay active
It's really important not to stop taking Ryeqo without speaking to your doctor first, as this could worsen your endometriosis symptoms. Your doctor can review your treatment plan and explore alternatives that may suit your body better.
A MyEndometriosisTeam member shared a similar experience, noting significant weight gain and hormonal disruption after starting a comparable treatment.
May 9
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