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Real members of MyEndometriosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have suspected endometriosis (I still need surgery to confirm it), and my pain has become debilitating. My doctor wants to try hormonal treatment options before considering anything surgical.

I’m honestly terrified of this option because I’m on multiple mood stabilizers for bipolar 2 disorder and have been stable for 5 years. I brought up my concerns, but I feel like they were brushed off. She basically told me that if one hormonal option doesn’t work, we’ll just move on to something even… read more

August 27
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A MyEndometriosisTeam Member

Hello! I’m so sorry you’re experiencing this, you’re not alone!

Something that has helped me without hormonal birth control are Pepcid and Allegra (antihistamines). I take them daily during the luteal phase, and while not a perfect or long-term solution, it has improved my overall mood.

September 2
A MyEndometriosisTeam Member

I found that the right birth control actually stabalized my mood more than my psych meds did. I had a hysterectomy and came off birth control thinking it would solve it and the hormonal fluctuations affecting my mood are really bad now despite being on the same psych meds that have stabalized me for years. I know how hard psych med changes are. I missed so much work when they were trying to stabalize my psych meds in the early days. The good news is that the birth control med changea are far less disruptive as they have far less chance of alergic reactions and severe debilitating side effects like the psych meds. I felt releif from both mood and pelvix pain for many years on a good birth control. If the doctor is willing to keep trying new options with you until you find one that works they may be more willing to help than it seemed at first but also trust your gut. It is important to feel like you will be herd if something isn't working. I did have to check in my my psychiatrist a lot because I take Lamictal which does get supressed by estrogen. It worked out such that in the withdrawl week of the pill the Lamictal worked stronger and the weels where the hormones were stable that helped manage the mood. I hope you find a good solution that works for you.

August 30
MyEndometriosisTeam

First of all, five years of stability is a huge achievement, and it makes complete sense to want to protect that. Your concerns are completely valid, and it's really frustrating when they feel dismissed.

You're definitely not alone in this. Many MyEndometriosisTeam members navigate the intersection of mental health and Show Full Answer

First of all, five years of stability is a huge achievement, and it makes complete sense to want to protect that. Your concerns are completely valid, and it's really frustrating when they feel dismissed.

You're definitely not alone in this. Many MyEndometriosisTeam members navigate the intersection of mental health and endometriosis treatment, and the emotional weight of managing both is very real. The connection between endometriosis and mental health is well-documented — chronic pain can worsen mood, and mood instability can worsen pain perception. It truly can become a difficult cycle. One important thing worth knowing: hormonal treatments are not all the same, and they affect people very differently. Options range from:

- Combined birth control (estrogen + progesterone) — pills, patches, or rings
- Progestin-only methods — pills, IUD, shot, or implant
- GnRH medications — which temporarily stop estrogen production but can cause mood-related side effects like hot flashes
- Danazol — a synthetic androgen that can also carry significant side effects

Some of these carry more mood-related risks than others, which is exactly why your concerns deserve a thorough conversation — not a brushoff. It may be worth asking for a collaborative conversation between your gynecologist and your psychiatrist before starting any hormonal treatment. Having both providers aligned on a plan could help protect your mental health stability while still addressing your endometriosis pain.

If your current doctor continues to dismiss your concerns, seeking a second opinion is always a reasonable and valid choice. You deserve a provider who treats your whole health picture — not just one piece of it. In the meantime, there are also non-hormonal ways to help manage endometriosis pain that could be explored alongside or while figuring out the hormonal piece:

- NSAIDs like ibuprofen or naproxen for pain relief
- Physical therapy
- Dietary changes
- Acupuncture
- Yoga

These won't treat the underlying condition, but they may help take the edge off while you and your care team work toward a plan that feels safe for your mental health too.

August 27

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