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A MyEndometriosisTeam Member asked a question 💭
Kitchener, ON

I’m slowly going through least medication options for painful ovulation. Unfortunately it was a no go for an IUD-didn’t help enough with pain management-tried Slynd which helped with the pain but I found I had very low mood, major hair loss and overall bloating. I’m two weeks in to Nextellis and feel okay aside from being surprisingly emotional 🖤 . I’m praying to find the right meds quickly as I have days that feel impossible.

2 days ago
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MyEndometriosisTeam

Finding the right hormonal treatment for endometriosis can feel like a frustrating journey — and you're definitely not alone in that. The emotional side effects you're noticing at two weeks in are worth keeping track of, as hormonal treatments can affect mood, especially in the early adjustment period.

Nextellis is a Show Full Answer

Finding the right hormonal treatment for endometriosis can feel like a frustrating journey — and you're definitely not alone in that. The emotional side effects you're noticing at two weeks in are worth keeping track of, as hormonal treatments can affect mood, especially in the early adjustment period.

Nextellis is a combined estrogen-progestin pill, which works by keeping hormone levels steady to help reduce painful ovulation and menstruation. This is a common approach since endometriosis is largely estrogen-dependent. Given your history with Slynd causing low mood, hair loss, and bloating, it's really important to keep a detailed log of any side effects you're experiencing now. This kind of record can be incredibly helpful when talking to your doctor. A MyEndometriosisTeam member shared that keeping a diary "steered doctors away from assumptions and helped focus on treating the endometriosis."

Some things worth tracking include:

- Mood changes — how frequent and how intense
- Physical symptoms — bloating, skin, hair
- Pain levels — is ovulation and period pain actually improving?
- Timing — when symptoms appear in your cycle If Nextellis doesn't work out, there are other hormonal options your doctor may consider, such as GnRH medications, which reduce estrogen production more directly. These come with their own side effects like hot flashes or bone density concerns, so they're typically discussed carefully with a doctor.

In the meantime, NSAIDs, heat therapy, and complementary options like acupuncture or TENS therapy can help manage pain on the harder days while you find your footing. Those impossible days are real — and you deserve relief. 🖤

2 days ago

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