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A MyEndometriosisTeam Member asked a question 💭
Halesowen, UK
August 13, 2020
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Answer Summary

Members shared mixed experiences with Depo Provera for managing endometriosis-related pain and bleeding, with some finding it helpful in... Read more

Members shared mixed experiences with Depo Provera for managing endometriosis-related pain and bleeding, with some finding it helpful in reducing symptoms post-surgery while others reported severe side effects including continuous heavy bleeding, significant weight gain (around 30 pounds within a year), and worsening pain. Several members described practical challenges like breakthrough bleeding between shots, the need to receive injections more frequently than the standard 12-week schedule, and ultimately combining Depo with other treatments like Mirena IUD or considering hysterectomy when symptoms persisted. A recurring theme was the importance of individual variation in response to treatment, the value of working with a vetted endometriosis specialist, and the struggle to balance avoiding major surgery with finding effective relief from debilitating period pain that severely impacts quality of life.

A MyEndometriosisTeam Member

I like drop initial until I gain 30pounds!

August 13, 2020
A MyEndometriosisTeam Member

I’m sorry you are experiencing so much pain. I had excision surgery just over a year ago and my doctor put me on depo after my first two period cycles because I continued to get ovulation pain in my remaining ovary. My pain/bleeding between depo shots aren’t nearly as bad as before surgery. I am unsure how bad the pain/bleeding would be if I wasn’t on depo but do think it helps.

Hopefully you can find a vetted endo specialist that can help you.

August 13, 2020 (edited)
A MyEndometriosisTeam Member

I’ve not had many side effects, which I was afraid it would. I’m am extremely sensitive to medication and have done really well on it. I’ve had weight grain with depo, but living in a pandemic probably doesn’t help. The one thing i will say I’ve experienced is that the depo only lasts 8 weeks and not 12 for me. I get my depo every 10 weeks but bleed heavily for 2 weeks sometimes longer. My doc is now suspecting I have adenomyosis. Next month, I’ll be getting mirena on top of depo as I am trying to delay having a hysterectomy. Let me know if I can help answer any other questions. Happy to help.

August 13, 2020 (edited)
A MyEndometriosisTeam Member

I've heard a lot of stories of people having negative experiences/side effects on lupron, so I'd encourage you to do a lot of research before you decide to commit to it. Much love <3

August 13, 2020
A MyEndometriosisTeam Member

Hi Taraleww, how have you been whilst on it. Ive heard alot of stories where it can make people feel worse..
Would you recommend it?xx

August 13, 2020

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