I am actually starting Lupron in a few weeks, but I was on Depo in my early 20s. While on depo, the only problem I had was that my period was never ending!! I had my period for an entire year before they decided to stop it due to it. I did not gain any weight on it.

@A MyEndometriosisTeam Member that is what I'm scared of I too just got my last shot of Lupron and I actually lost almost 30 lbs on it but afraid the depo shit will make me gain

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A MyEndom...

I just came off of 6 months of Lupron and got my first Depo yesterday. I didn't gain any weight on Lupron, thankfully. But, I'm worried that I will on Depo. Has anyone had this problem? I'm really hoping to lose weight now that I'm having less pain.

The pain of endo did get much better but the nausea and bone pain kicked my butt

I had gained 70 pounds in 6 months due to the Lupron and I was constantly snacking. The only good thing about it was that it eased my pain away